藿朴夏芩汤治疗小儿功能性消化不良随机平行对照研究

Huo Pu Xia Qinlian Decoction in the Treatment of Children with Functional Dyspepsia Randomized Parallel Controlled Study

[目的]观察藿朴夏芩汤治疗小儿功能性消化不良疗效。[方法]使用随机平行对照方法,将78例住院及门诊患者按随机数字表法分为两组。对照组39例吗丁啉,8~10mg/次,3次/d,餐前30min口服。治疗组39例藿朴夏芩汤(藿香、黄芩、枳壳、广木香、半夏各8g,厚朴6g,茯苓10g,蒲公英15g,砂仁3g;呕恶加竹茹8g,生姜2片;嗳气加沉香3g,枳壳8g;大便溏薄加焦六粬、焦山楂各8g;纳呆加鸡内金8g,炒谷芽、炒麦芽各12g;腹痛加甘松6g,元胡10g);1剂/d,水煎300mL,2次/d。连续治疗7d为1疗程。观测临床症状、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组显著缓解25例,中度缓解5例,轻度缓解6例,无效3例,总有效率92.37%。对照组显著缓解15例,中度缓解5例,轻度缓解6例,无效13例,总有效率66.67%。治疗组疗效优于对照组(P【0.05)。[结论]藿朴夏芩汤治疗小儿功能性消化不良效果显著,值得推广。

[Objective]To observe the adverse effect of Huo Pu Xia Qin Decoction Treatment of children with functional dyspepsia.[Methods]Using randomized controlled methods,78 cases of inpatient and outpatient were randomly divided into two groups. A control group of 39 cases of domperidone,8mg ~10mg/,3 /d,30min before meal oral. The treatment group of 39 cases of Huopu Xia Qin Decoction(Huoxiang,Huangceng,Jike,Guangmuxiang,Banxia each 8g,Houbu 6g,Fuling 10g,Pugongying 15g,Sharen 3g,vomiting add Zhuru 10g,2 pieces of ginger;belching plus Chenxiang 3g,Jike 8g;thin stool add Jiaoliuqu,Jiaoshanzha each 8g;anorexia add Jineijin 10g,Chaoguya,Chaomaiya each 12g,abdominal pain add Gansong6g,Yuanhu 10g). 1 doses of /d,water simmer in water 300mL,sooner or later oral. Continuous treatment with 7d for 1 courses. Observation of clinical symptoms,adverse reaction. Continuous treatment of 4 courses,to judge the curative effect.[Results]the treatment group was significantly relieved in 25 cases,moderate remission in 5 cases,mild remission in 6 cases,3 cases ineffective,the total efficiency of 92.37%. The control group was significantly relieved in 15 cases,moderate remission in 5 cases,mild remission in 6 cases,13 cases ineffective,the total efficiency of 66.67%. The treatment group was better than control group(P< 0.05).[Conclusion]Huopu summer Qinlian Decoction in the treatment of children with functional dyspepsia effect is significant,worthy of promotion.