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养血清脑颗粒联合西药治疗高血压脑出血随机平行对照研究 被引量:1

Yangxueqingnao Particles Combined with Western Medicine Treatment of Hypertensive Cerebral Hemorrhage Randomized Parallel Controlled Study
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摘要 [目的]观察养血清脑颗粒联合西药治疗高血压脑出血疗效。[方法]使用随机平行对照方法,将84例住院患者按随机数字表法分为两组。降压、脱水及营养支持等常规治疗,病情稳定,高压氧疗。对照组42例安慰剂(淀粉、炭黑色素、苦味素),2.0g/次,3次/d,口服。治疗组42例养血清脑颗粒,4.0g/次,3次/d,口服。连续治疗21d为1疗程。观测临床症状、GCS评分、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈5例,显效10例,有效17例,无效10例,总有效率76.20%。对照组痊愈2例,显效5例,有效11例,无效24例,总有效率42.90%。治疗组疗效优于对照组(P<0.01)。GCS积分两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]养血清脑颗粒联合西药治疗高血压脑出血效果显著,值得推广。 [Objective]To observe the Yangxueqingnao particles combined with western medicine treatment of hypertensive cerebral hemorrhage. [Methods]Using randomized controlled methods, will be divided into two groups according to the random number table, 84 cases of hospitalized patients. The routine antihypertensive treatment, dehydration and nutritional support, after the disease tends to be stable, given hyperbaric oxygen therapy. 42 cases in the control group(placebo ingredient is starch, self-made carbon black pigment, bitter), 2.0g/, 3 /d, oral. The treatment group of 42 cases raise serum brain granule, 4.0g/, 3 /d, oral. Observation of clinical curative effect, GCS score, adverse reaction. 21d for 1 courses, 1 courses of treatment(21d), curative effect.[Results]The treatment group cured 5 cases, effective in 10 cases, effective 17 cases, invalid 10 cases, the total efficiency of 76.20%. The control group cured 2 cases, effective in 5 cases, effective 11 cases, invalid 24 cases, the total efficiency of 42.90%. The treatment group was better than control group(P < 0.01). GCS scores were improved(P< 0.01), the treatment group than the control group(P< 0.01). Two groups of liver and renal function and the blood and urine routine examination results were normal, and there was no special discomfort associated with drugs. To observe the process of two groups were no serious adverse events. [Conclusion]The effect of Yangxueqingnao particles combined with western medicine treatment of hypertensive cerebral hemorrhage was cerebral, worthy of promotion.
作者 秦松 黄爱娟
出处 《实用中医内科杂志》 2013年第8S期9-10,共2页 Journal of Practical Traditional Chinese Internal Medicine
关键词 高血压脑出血 养血清脑颗粒 安慰剂 GCS评分 随机平行对照研究 Hypertensive cerebral hemorrhage Yangxueqingnao Granule Placebo GCS score Randomized parallel controlled study
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