乌头汤治疗风湿痹症随机平行对照研究

Aconite Decoction in the Treatment of Rheumatism of Random Parallel Control

[目的]观察乌头汤治疗风湿痹症疗效。[方法]使用随机平行对照方法,将120例住院及门诊患者按就诊顺序编号法分为两组。对照组60例来氟米特,前3d,50mg/次;3d后,10mg/次,1次/d,睡前口服。治疗组60例乌头汤(甘草、干姜、桂枝各10g,威灵仙15g,防风、清风藤各20g,制川乌9g,黄芪12g,芍药、麻黄各3g),1剂/d,水煎200mL,早晚口服。两组均连续治疗30d为1疗程。观测临床症状、关节疼痛、关节功能、不良反应。治疗1疗程,判定疗效。[结果]治疗组治愈50例,显效6例,有效3例,无效1例,总有效率98.33%。对照组治愈22例,显效3例,有效7例,无效18例,总有效率70.00%。治疗组疗效优于对照组(P<0.05)。[结论]乌头汤治疗风湿痹症效果显著,值得推广使用。

[Objective]To observe the curative effect of Aconite Decoction in the treatment of rheumatism. [Methods]Using randomized controlled methods, 120 cases of inpatients and outpatients number were randomLy divided into two groups. A control group of 60 cases of leflunomide, three days ago, 50mg/; 3 days later, 10mg/; 1 /d, orally at bedtime. The treatment group of 60 cases of Aconite Decoction(Gancao, Ganjiang,Guizhi each 10g,Weilingxian 15g,Fanfeng,Qingfengteng each 20g,Zhichuanwu 9g,Huangqi 12g,Shaoyao,Huangma each 3g.). 1 doses of /d, water simmer in water 200mL, sooner or later oral. The two groups were continuous treatment with 30d for 1 courses. Observation of clinical curative effect, adverse reaction. 1 courses of treatment, the curative effect. [Results]The treatment group cured 50 cases, effective in 6 cases, effective 3 cases, invalid 1 cases, the total efficiency of 98.33%. The control group 22 cases were cured, 3 cases markedly effective, effective 7 cases, invalid 18 cases, the total efficiency of 70%. The treatment group was better than control group(P< 0.05).[Conclusion]Aconite Decoction in the treatment of rheumatism effect is significant, worthy of popularization.