银杏叶提取物联合西药治疗脑梗塞随机平行对照研究

Ginkgo Biloba Extract Injection Combined Random Parallel Control Study Western Medicine Treatment of Cerebral Infarction

[目的]观察银杏叶提取物联合西药治疗脑梗塞疗效。[方法]使用随机平行对照方法,将38例住院患者按掷骰子法随机分为两组。对照组19例常规西药治疗,低分子右旋糖酐、肠溶阿司匹林、尼群地平及胞二磷胆碱改善脑部血液循环及脑功能。治疗组19例银杏叶提取物87.5mg+5%葡萄糖250mL,静滴,1次/d。按病情脱水、降压、降脂、降糖处理。西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、血液流变学指标、不良反应。连续治疗2疗程(28d),判定疗效。[结果]治疗组痊愈10例,显效5例,有效3例,无效1例,总有效率94.74%。对照组痊愈6例,显效4例,有效5例,无效4例,总有效率78.95%。治疗组疗效优于对照组(P<0.05)。血液流变学指标均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]银杏叶提取物注射液联合西药治疗脑梗塞效果显著,值得推广。

[Objective]To observe the ginkgo biloba extract injection combined western medicine curative effect on cerebral infarction.[Methods]Using random parallel control method, 38 cases of hospitalized patients were randomly divided into two groups according to roll the dice method. Control group 19 cases of internal conventional western medicine treatment, including the application of low molecular dextran, enteric aspirin group, horizon and cytidine diphosphate choline improve blood circulation and brain function. Treatment group(19 cases) and ginkgo biloba extract injection of 87.5 mg+5% glucose 250ml, static drop 1/d. According to the condition to dehydration, step-down, lipid-lowering, hypoglycemic treatment. Blood tests before and after treatment the blood rheology indexes. Western medicine treatment with the control group. Continuous treatment of 14d to 1 course of treatment. Observation of clinical symptoms, blood rheology indexes, adverse reactions. Continuous treatment 2 period of treatment(28d), to determine efficacy.[Results]The treatment group, 10 cases were cured, 5 cases were markedly improved, 3 cases ineffective in 1 case, and the total effective rate was 94.74%. Control group cure 6 cases, 4 cases were markedly effective, effective in 5 cases, 4 cases were invalid, the total effective rate was 78.95%. The treatment group curative effect is better than that of control group(P <0.05). Could improve the blood rheology indexes(P<0.05), the treatment group improved better than that of control group(P<0.05).Ginkgo biloba extract injection.[Conclusion]Combined western medicine treatment of cerebral infarction effect is remarkable, is worth promoting.