大黄胃管注入联合奥曲肽治疗急性胰腺炎随机平行对照研究

Rhubarb Stomach Tube Joint Mr Qu Peptide Injection in Treatment of Acute Pancreatitis Random Parallel Control Study

[目的]观察大黄胃管注入联合奥曲肽治疗急性胰腺炎疗效。[方法]使用随机平行对照方法,将30例住院患者按抛硬币法随机分为两组。禁水、禁食、抑酸、控感染、减压肠胃等支持性治疗。对照组15例奥曲肽,0.1mg/次,1次/8h,3d后改为1次/d,皮注。重症患者0.6mg/次,1次/8h,病情缓解后0.1mg/次,1次/8h。治疗组15例20g大黄泡水,由胃管注入,2次/d。西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、血、尿淀粉酶、不良反应。治疗1疗程(7d),判定疗效。[结果]治疗组显效7例,有效7例,无效1例,总有效率93.33%。对照组显效3例,有效8例,无效4例,总有效率84.61%。治疗组疗效优于对照组(P<0.05)。观察指标治疗组改善优于对照组(P<0.05)。[结论]大黄胃管注入联合奥曲肽治疗急性胰腺炎效果显著,值得推广。

[Objective]To observe the rhubarb combined the peptide curative effect in treatment of acute pancreatitis.[Methods]Using random parallel control method,30 patients hospitalized patients were randomly divided into two groups according to flip a coin method.Ban water,fasting,acid suppression,infection control,such as stress gastrointestinal supportive treatment.The control group of 15 cases of the peptide,0.1 mg/time,1/8 h,3 d instead of 1/d,after skin note.Critically ill patients with 0.6 mg/times,1 times/8h,after remission in 0.1 mg/times,18 times/h.Rhubarb treatment group(15 cases of 20 g bubble water,by stomach tube injection,2 times/d.Western medicine treatment with the control group.Continuous treatment of 7d for 1 course of treatment.Observation of clinical symptoms,observation index,adverse reactions.Treatment as a course(7d),to determine efficacy.[Results]The treatment group 7 cases were markedly effective,effective 7 cases,1 had no effect,the total effective rate was 93.33%.Control group 3 cases had marked effect,8 cases,4 cases were invalid,the total effective rate was 84.61%.The treatment group curative effect is better than that of control group(P<0.05).To observe the treatment group improved than the control group(P<0.05).[Conclusion] Rhubarb joint the octreotide in treatment of acute pancreatitis effect is remarkable,is worth promoting.