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降钙素增强双膦酸盐对绝经后骨质疏松患者慢性腰背痛缓解及生活质量改善的作用分析 被引量:1

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摘要 目的分析依降钙素联合利塞膦酸钠对绝经后骨质疏松患者慢性腰背痛缓解及生活质量改善的作用。方法研究开展于2016年1—10月,选取该院收治的60例绝经后骨质疏松患者,随机将其分为B组(n=30)与A组(n=30),B组单纯使用利塞膦酸钠治疗,A组应用利塞膦酸钠+依降钙素治疗,对比两组患者的治疗后主观疼痛程度与生活质量。结果在治疗后6个月后,两组患者骨质疏松疼痛均有所缓解,A组疼痛改善程度明显优于B组,组间比较差异有统计学意义(P<0.05);对比两组患者治疗后生活质量改善情况,A组与B组差异有统计学意义(P<0.05)。结论对绝经后骨质疏松患者采用降钙素增强双膦酸盐治疗,可有效缓解患者慢性腰背酸痛体征,提高患者的生活质量,适合临床应用与推广。
作者 李秀英
出处 《双足与保健》 2017年第8期110-,112,共2页 Biped and Health
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  • 1蒋晔,丁翔宇,蒋懿,郝福,李艳荣.雷尼酸锶药效学与药动学的研究进展[J].中国医院药学杂志,2006,26(2):197-199. 被引量:6
  • 2Briot K, Benhamou CL, Roux C. Hip cortical thickness as- sessment in postmenopausal women with osteoporosis and strontium ranelate effect on hip geometry[J]. J Clin Densit- om,2012,15(2) : 176-85.
  • 3Boyd SK, Szabo E, Ammann P. Increased bone strength is as- sociated with improved bone microarchiteeture in intact female rats treated with strontium ranelate., a finite element analysis study[J]. Bone,20l1,48(5) : 1109-1116.
  • 4Geoffroy V, Chappard D, Marty C, et al. Strontium ranelate decreases the incidence of new caudal vertebral fractures in a growing mouse model with spontaneous fractures by improving bone mieroarehitecture[J].Osteoporos Int, 2011,22 ( 1 ) : 289- 297.
  • 5Meunier P J, Roux C, Seeman E,et al. The effects of stronti um ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis[J]. N Engl J Med, 2004, 350 (5) :459-468.
  • 6Meunier PJ, Roux C, Ortolani S, et al. Effects of long-term strontium ranelate treatment on vertebral fracture risk in post- menopausal women with osteoporosis[J]. Osteoporos Int, 2009,20(10) : 1663-1673.
  • 7Kanis JA, Johansson H, Oden A, et al. A meta-analysis of the effect of strontium ranelate on the risk ot" vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAXR[J].Osteoporos Int, 2(111,22 (8) : 2347-2355.
  • 8Reginster JY, Kaufman JM, Goemaere S, et al. Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis[J].Osteoporos Int,2012,23(3) : 1115-1122.
  • 9Ziller V, Kostev K, Kyvernitakis I, et al. Persistence and compliance of medications used in the treatment of osteoporosis a analysis using a large scale, representative, longitudinal Ger- man database [J]. Int J Clin Pharmacol Ther, 2012, 50 (5):315-322.
  • 10YU Changlong. Orthopaedic Rehabilitation[M].Beijing:People ’ s Medical Publishing House,2010.866-877.

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