小儿手足口病免疫球蛋白和超敏C反应蛋白的临床检验分析

Clinical Analysis of Immunoglobulin and High Sensitivity C Reactive Protein in Hand Foot and Mouth Disease in Children

目的探究小儿手足口病免疫球蛋白和超敏C反应蛋白的临床检验情况。方法针对40例小儿手足口病患儿进行免疫球蛋白和超敏C反应蛋白检验,并归为观察组,针对另外40名健康体检者进行相同检验,并归为对照组;对比分析两组检查结果,入选者均为该院2016年2月—2017年1月间收治。结果比较两组超敏C反应蛋白水平,可见两组差异有统计学意义,其中观察组超敏C反应蛋白水平为(10.68±3.69)μg/mL,对照组为(1.14±0.26)μg/mL;比较两组免疫球蛋白水平,包括IgM、IgG、IgA等,可见两组差异有统计学意义(P<0.05)。结论小儿手足口病免疫球蛋白和超敏C反应蛋白的临床检验分析发现,其能够明确反应出患儿的病变情况,且和正常的健康者比较存在明显差异,因此免疫球蛋白和超敏C反应蛋白检验值得在小儿手足口病诊断的过程中使用。

Objective To explore clinical examination of children with HFMD immunoglpbulin and hypersensitive C reactive protein. Methods 40 cases of children with HFMD patients with immunoglobulin and high sensitivity C reactive protein test, and classified as the observation group, the same test for another 40 healthy persons, and classified as the control group; analysis of the test results of two groups were compared, selected in our hospital from February 2016 to January 2017. Results High sensitivity C reactive protein levels between the two groups, the two groups have obvious difference, the observation group of high sensitivity C reactive protein level of(10.68±3.69)μg/mL. Control group was(1.14±0.26)μg/mL; immunoglobulin levels were compared between the two groups including IgM, IgG, IgA, the two groups have obvious difference; comparison between groups showed significant difference(P<0.05). Conclusion The clinical examination of children with HFMD immunoglobulin and high sensitivity C reactive protein analysis showed that it can clearly reflect pathological changes of patients and normal healthy subjects, and relatively obvious difference, so the use of immunoglobulin and hypersensitive C reactive protein test is in the diagnosis of pediatric HFMD.