玻璃酸钠治疗膝关节骨性关节炎疗效观察

Efficacy of Sodium Hyaluronate in the Treatment of Knee Osteoarthritis

目的探讨玻璃酸钠治疗膝关节骨性关节炎的临床疗效。方法采用回顾性分析的方法,对2015年6月—2016年6月就诊的38例膝关节骨性关节炎患者,采用随机分组的方式分成对照组和治疗组,每组19例。对照组患者采取口服氨基葡萄糖进行治疗,治疗组在对照组口服氨基葡萄糖治疗的基础上,采用关节腔注射玻璃酸钠注射液进行治疗,比较两组患者的临床疗效。结果对照组治疗的总体有效率为73.68%,治疗组的总体有效率为94.74%,对比差异有统计学意义(P<0.05);治疗组在治疗后3、6、9个月的膝关节功能恢复评分显著优于对照组;生活质量的评分低于对照组,均差异有统计学意义(P<0.05)。结论玻璃酸钠注射液用于治疗骨性关节炎效果较好,能显著改善膝关节功能,提升患者生活质量,值得临床推广应用。

Objective To observe the therapeutic effect of sodium hyaluronate in the treatment of knee osteoarthritis.Methods a retrospective analysis of the June 2015 to June 2016 was performed on 38 patients with kniee obsecarthritis who were hospitalized, were randomly divided into control group and treatment group, 19 cases in each group. The control group were treated with oral glucosamine treatment, the treatment group in the control group based on the treatment of oral glucosamine, the intra-articular injection of Sodium Hyaluronate Injection for treatment, the clinical curative effect of two groups were compared. Results The control group total effective rate of treatment was 73.68%, treatment group totalBody efficiency is 94.74%, and there were significant correlation(P<0.05); the treatment group was significantly better than the control group in the scores of knee function recovery 3,6,9 months after treatment; the quality of life score lower than the control group, were statistically significant(P<0.05). Conclusion Sodium Hyaluronate Injection for the treatment of osteoarthritis with good effect, can significantly improve knee function, improve the quality of life of patients, worthy of clinical application.