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ICU泛耐药鲍曼不动杆菌感染联合用药效果 被引量:2

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摘要 目的:探讨头孢哌酮–舒巴坦结合替加环素治疗ICU泛耐药鲍曼不动杆菌感染的效果及药学分析。方法:选取2015年10月至2017年10月南阳市第二人民医院收治的ICU泛耐药鲍曼不动杆菌感染患者300例纳入本研究工作并划分为两组。对照组采用替加环素治疗,观察组采用头孢哌酮–舒巴坦结合替加环素治疗。结果:观察组患者治疗总有效率(86.00%)、细菌清除率(62.00%)高于对照组,而不良反应发生率(3.33%)、细菌未清除率(28.00%)、细菌再感染率(0.00%)低于对照组,差异具有统计学意义(P <0.05);治疗前两组患者白细胞计数、血清白蛋白、C反应蛋白、APACHEⅡ评分、体温、氧合指数比较,差异均无统计学意义(P> 0.05);治疗后两组均有改善,观察组改善幅度更明显比较,差异具有统计学意义(P <0.05)。结论:头孢哌酮–舒巴坦结合替加环素治疗泛耐药鲍曼不动杆菌感染的效果明显,不良反应发生率低,细菌清除率高,细菌再感染发生率低,且可以明显改善患者的相关症状。
出处 《深圳中西医结合杂志》 2019年第5期137-138,共2页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
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