奥美拉唑治疗消化性溃疡的疗效及不良反应观察

OBSERVATION OF THE THERAPEUTIC AND SIDE EFFECTS OF OMEPRAZOLE ON PEPTIC ULCER

目的 探讨奥美拉唑治疗消化性溃疡的效果及不良反应的发生情况 ,以便指导临床用药。方法 对比分析奥美拉唑与雷尼替丁治疗消化性溃疡的疗效及不良反应。结果 奥美拉唑组的治疗效果明显优于雷尼替丁组 (P <0 .0 1) ;而不良反应明显低于雷尼替丁组 (P <0 .0 1)。结论 奥美拉唑是目前临床治疗消化性溃疡最安全有效的药物 。

Objective To explore the therapeutic and side effects of omeprazole on peptic ulcer for the purpose of clinical drug application.Methods Comparative analyses of the therapeutic and side effects of omeprazole and ranitidine on peptic ulcer were made.Results Better curative effects and less side effects were got with omeprazole than ranitidine(P<0.01).Conclusion Omeprazole has proven to be a safe and effective drug in the treatment of peptic ulcer and deserves to be popularized clinically.