南方医院头孢菌素类药物使用情况调查

The situation of use of cephalosporins in Nanfang Hospital

目的 :评估本院门诊药房头孢菌素类抗生素的使用情况。方法 :随机抽取门诊处方 2 5 2 32张 ,收集含头孢菌素类药物处方 2 394张 ,进行科室、年龄分布、药物利用指数、用药天数、抗微生物药物联合用药等的统计分析。 结果 :一代、二代、三代头孢菌素类抗生素使用频率分别为 5 8.1%、13.2 %、2 8.7% ;病人年龄分布广泛 (6 d～ 88岁 ) ;人均使用头孢菌素类药物天数为 (4.73± 3.79) d;头孢菌素类药物与其他抗微生物药物人均联合使用数为 (1.38± 0 .5 7)种 ;部分头孢菌素类药物药物利用指数偏低。 结论 :我院头孢菌素类抗生素用于婴幼儿较普遍 ;有相当大的比例与抗病毒药联合使用 ,欠合理 ;部分头孢菌素类药物的用量不足 。

Objective: To evalua te the situation of using cephalosporins for outpatients in our hospital. Methods: Twenty-five thousand two hundred and thirty-two prescriptions i n 21 d from April 2002 to June 2002 were collected randomly, of which cephal ospo rins prescriptions were 2 394. The distribution of clinical departments, age, dr ug utilization index (DUI), days of administration and combined use of antimicrobial agents were analyzed. Results: Frequency of use of 1st generation,2nd generation and 3rd generation of cephalosporins were 58 1% ,13.2% and 28 7%, respectively. The distribution of age was from 6 d to 88 yea rs. The mean duration of administration was (4.73±3.79) d. The mean number of combined use with other antimicrobial agents per patient was (1.38±0.57). The DUI of some drugs was low. Conclusion: It is common to use cephalos p orins in infant and child patients in this hospital. In a considerable proportio n of cases in this hospital cephalosporins were used in combination with antivir al drugs, but this is unreasonable. DUI shows that some drugs are insufficient i n dose.