铅性肾病的生物标志物研究

Advance in research on biomarkers of lead-induced nephropathy

铅是常见的环境污染物 ,生物标志物是反映机体与环境因子 (物理的、化学的或生物的 )交互作用所引起的所有可测定的改变 ,它可以反映机体对毒物的接触程度、早期毒效应以及不同个体对毒物的敏感性。本文从接触标志物、效应标志物。

Lead is a common pollutant metal in our environment.Biomarkers reflect all the measurable changes caused by interaction of human bodies with environmental factors,including physical,chemical and biological ones.Biomarkers can be used in measuring exposure,detecting early biological effect and individual susceptibility of human bodies.Researches on biomarkers of lead-induced nephropathy reflecting its exposure,biological effects and individual susceptibility and mechanism,treatment and prevention of nephropathy were reviewed in this paper.