康欣胶囊对血管性痴呆影响的临床观察

Clinical observation of Kangxin Capsule on the influence of vascular dementia

目的 观察康欣胶囊对血管性痴呆 (VD)患者影响的有效性和安全性。方法 依据诊断标准选取 VD患者 63例 ,随机分为治疗组(33例 )和对照组 (30例 ) ,观察患者治疗前后的变化。结果 康欣胶囊能有效改善 VD患者中医证候 ,显著降低 HCY、β- AP水平 (P<0 .0 1 ) ,且未发现明显毒副作用。结论 康欣胶囊是安全有效治疗 VD的中药制剂。

Objective To observe Kangxin capsules' effectiveness and safety in treating vascular dementia.Methods Patients selected according to the diagnostic standard were randomly divided into two groups. The treatment group (33 cases) was treated with Kangxin capsule and the control group (30 cases) with hydergine.Results Kangxin capsule could ameliorate the clinical syndrome of TCM, significantly decreased the level of homocysteine and β amyloid protein( P <0.01),and no toxic adverse reaction was found in the observation period.Conclusions Kangxin capsules can safely and effectively treat.