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Expression of HSP70 in Peripheral Lymphocytes of the Patients with Allergic Rhinitis

Expression of HSP70 in Peripheral Lymphocytes of the Patients with Allergic Rhinitis
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摘要 The expression levels of heat shock protein 70 (HSP70) from peripheral lymphocytes of the patients with allergic rhinitis (AR) and the clinical implication were investigated In the morning, 3 ml of fasting venous blood was taken out The lymphocytes were isolated by using Ficoll-Hypaque and the expression of HSP70 in the lymphocytes was detected by using Western blot In the AR patients the HSP70 level (41 49±15 77 integrated optical density, IOD) were significantly higher than that in the control group (23 89±10 13 IOD, P< 0 05) Western blot demonstrated that HSP70 bands in AR patients were more intensive than those in the control group It was concluded that the elevated HSP70 level in peripheral lymphocytes of the AR patients might contribute to the development of AR The expression levels of heat shock protein 70 (HSP70) from peripheral lymphocytes of the patients with allergic rhinitis (AR) and the clinical implication were investigated In the morning, 3 ml of fasting venous blood was taken out The lymphocytes were isolated by using Ficoll-Hypaque and the expression of HSP70 in the lymphocytes was detected by using Western blot In the AR patients the HSP70 level (41 49±15 77 integrated optical density, IOD) were significantly higher than that in the control group (23 89±10 13 IOD, P< 0 05) Western blot demonstrated that HSP70 bands in AR patients were more intensive than those in the control group It was concluded that the elevated HSP70 level in peripheral lymphocytes of the AR patients might contribute to the development of AR
出处 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2003年第3期310-312,共3页 华中科技大学学报(医学英德文版)
关键词 allergic rhinitis LYMPHOCYTE heat shock protein 70 allergic rhinitis lymphocyte heat shock protein 70
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