C反应蛋白与缺血性脑卒中预后关系的探讨

Exploration on the relationship between C-reactive protein and consequence of ischemic stroke

目的 :探讨C反应蛋白 (CRP)与急性缺血性脑卒中预后的关系。方法 :应用免疫浊度法对住院的首次急性缺血性脑卒中患者 96例、5 0例非脑卒中患者血清C反应蛋白进行测定 ,并随访观察一年。结果 :缺血性脑卒中患者的CRP为 (1 4 85± 7 2 4 )mg L ,明显高于对照组 (4 75± 1 70 )mg L(P <0 0 1 ) ,大、中梗死组及中、重型组CRP明显高于小梗死组、轻型组CRP(P<0 0 1 ) ;而复发脑卒中及死亡者的CRP均明显高于预后好的患者 (P <0 0 1 )。结论 :CRP可作为预测急性缺血性脑卒中预后的指标之一。

Objective:To explore the relationship between C reactive protein(CRP) and consequence of acute ischemic stroke.Methods:Immunoelec nephelometry turbidimetry were used to measure the content of CRP in 96 patient with initial ischemic stroke and in 50 cases of non stroke control group,and follow up time was one year.Results:The content of CRP(14 85±7 24mg/L) in patients with ischemic stroke were significantly higher than those(4 75±1 70mg/L)in control group(P<0 01),the content of CRP in extensive infarction,middle infarction and moderate type group,severe type group were significantly higher than those in small infarction,mild type group(P<0 01).The content of CRP in recurrent ischemic stroke and the dead group were significartly higher than those in good consequence group(P<0 01).Conclusion:CRP can be a marker for calculating the consequence of ischemic stroke.