牛磺酸对染铅大鼠体重及学习记忆的影响

Effect of Taurine on Body Weight and Learning and Memory Ability of Lead Exposed Rats

目的 探讨牛磺酸拮抗铅损害神经系统的作用。方法 采用测量体重增量和Y型迷宫实验 ,观察饮用含不同浓度醋酸铅 (0 0 2 ,0 2g/L)的水和含不同剂量牛磺酸 (5 ,10 g/kg)饲料喂养的大鼠 ,与饮用单蒸水和普通饲料喂养的大鼠之间体重增量和学习记忆能力的差别。结果 牛磺酸能明显促进染铅大鼠体重增加及学习记忆能力增强。结论 牛磺酸对铅损害神经系统有明显的拮抗作用。

Objective To explore the resistant effect of taurine on the injury of nervous system induced by lead.Methods Measurement of body weight increase and Y labyrinth test were adopted.Different desage of lead acetate(0 02,0 2 g/L)in water solution,and different dosage of taurine(5,10 g/kg)in feed were fed to investigate the body weight increase and changes in learning and memory ablility.Results Taurine could remarkably increase the body weight of rats and enhance their learning and memory abliity.Conclusions Taurine might distinctively resist the injury of nervous system induced by lead.