氟化物涂膜后唾液氟浓度的变化

Fluoride Concentration in Saliva after Use of Fluoride Varnish

目的观察并比较使用氟化物涂膜及氟化钠溶液后,唾液中氟离子浓度的变化。方法选取20例5岁儿童,随机分为氟化钠涂膜组和氟化钠溶液组,每组10例。使用氟化物前及使用后0.25h、0.5h、1h、2h、6h、12h、24h分别留取非刺激性全唾液,唾液离心后用氟离子选择电极法测定唾液中的氟离子浓度。结果使用氟化钠涂膜后0.25h、0.5h、1h、2h、6h,唾液中氟离子浓度高于用氟前;使用后0.5～6h,唾液中氟离子浓度高于使用氟化钠溶液组。结论氟化钠涂膜与氟化钠溶液相比,能延长氟化物和牙釉质接触的时间和浓度。

Objective The purpose of this vivo study was to compare fluoride conce nt ration in saliva of patients treated with fluoride varnish and fluoride solution .Methods205-year-old children were selected and divided into fluoride var-nish and fluoride solution groups.The samples of unstimulated whole saliva were colle cted at base-line before and after0.25h,0.5h,1h,2h,6h,12h,24h treatment wi th fluoride varnish and fluoride solution.Saliva fluoride concentrations were me asured using an ion-specific electrode.Results After0.25h,0.5h,1h,2h,6h trea tment with fluoride varnish,the val-ues of salivary fluoride concentration were higher than baseline,the values of fluoride varnish group were higher than tho se in fluoride solution group after0.5h to6h.Conclusions Compared with fluoride solution,fluoride varnish main-tained a longer time of high salivary fluoride c oncentration.