整体型氯己啶控释系统根管消毒作用的初步临床观察

Preliminary clinical study of endodontic antiseptic in monotithic type chlorhexidine controlled release delivery system

对整体型氯已啶控释系统的根管消毒作用进行了初步临床观察，２４位志愿受试者中１２颗患牙封入整体型氯己啶系统，另１２例常规封甲醛甲酚棉捻，５天后细菌学检查结果表明整体型氯己啶控释系统根管消毒作用明显优于甲醛甲酚，卡方检验有显著性差异。提示整体型氯己啶控释系统可以其良好的根管消毒效果，作为一种新药剂型广泛用于临床治疗。

The purpose of clinical study was to assess the bacteriological status of the root canal after disinfection with thd monotithic type chlorhexidine enrolled release delivery system(CCROS).In experiments the monotithic type CCRDS was fround to be more effective than the reservoir type CCRDS.The root canals of 24 teeth with apical periodontitis were completely instrumented and irrigated with sodium hypochloride.After the instrumentations,12 teeth were treated with the monotithic type CCRDS,12 teeth were treated with formocresol.Bacterological samples from the root canals were taken after 5 days using an anaerobic technique. The results indicated that monotithic type CCRDS was more effective than formocresol in obtaining bacteriafree root canals(Chi-square test P<0.05).The advantages of an antiseptic with along lasting effect for the elimination of bacteria form the root canal and for the prevention of reinfection were emphasized.