2Hopwood D A, Chater K F. Fresh approaches to antibiotic production[J]. Philos Trans R Soc Lond B Biol Sci, 1980,290(1040) :313.
3Hopwood D A. Antibiotics: opportunities for genetic manipulation[J]. Philos Trans R Soc Lond B Biol Sci,1989,324(1224) :549.
4Hopwood D A. Towards on understanding of gene switching in Streptornyces, the basis of sporulation and antibiotics production[J]. Proc R Soc Lond(Biol), 1988 , 235 :121.
5Horininchi S, Hara O, Beppu T, et al. Cloning of a pleiotropic gene that positively controls biosynthesis of A - factor, Actinorhodin and Prodigiosin in Streptomyces coelicolor A3 (2) and Streptomyces lividans [ J]. J Bacteriol, 1983,155(3) : 1238.
6Jones G H, Hopwood D A. Molecular cloning and expression of the phenoxazinone synthase gene from S. antibioticus [J]. J Biol Chem, 1984,259(22) : 14151.
7Jones G H, Hopwood D A. Activation of phenoxazinone synthase expression in Streptomyces lividans by cloned DNA sequences for Streptomyces antibioticus[J]. J Biol Chem, 1984,259(22) : 14158.
8Yamashita F,Hotta K, kaxasance S, et al. New antibiotic - producing Streptomyces selected by antibiotic resistance as a maker. I.New antibiotic production generated by protoplast fusion treatment between Streptomyces griseus and Streptomyces tenjimariensis [J]. J Antibior , 1985,38(1) : 58.
9Hutchinson C R, Borell C W, Otten S L, et al. Drug discovery and development through the genetic engineering of antibiotic—production microorganisms [J]. J Med Chem, 1989,32(5): 929.
