期刊文献+

缺血性脑血管病病人sIL-2R的检测

DETECTION OF SERUM SOLUBLE INTERLEUKIN-2 RECEPTOR IN PATIENTS WITH ISCHEMIC CEREBRAL VASCULAR DISEASE
下载PDF
导出
摘要 ①目的 探讨缺血性脑血管病 (ICVD)病人的发病与可溶性白细胞介素 2受体 (sIL 2R)水平的关系。②方法 采用ELISA法对 6 9例ICVD病人及 4 3例正常对照者血浆sIL 2R水平进行检测。③结果 ICVD病人sIL 2R水平明显高于正常对照组 (t=6 .4 90 ,P <0 .0 1)。④结论 ICVD病人体内可能存在着一定的免疫异常。对ICVD病人免疫治疗可能有效。 Objective To investigate the relationship between the occurrence of ischemic cerebral vascular diseases(ICVD) and the level of serum soluble interleukin-2 receptors(sIL-2R) in patients with ICVD. Methods The level of serum sIL-2R in 69 patients with ICVD and 43 cases of normal control was assayed with ELESA. Results The level of serum sIL-2R in the ICVD patients was significantly higher than that in the normal controls (t=6.490, P<0.01). Conclusion The pathogenesis of ICVD might be associated with immunity. An immunotherapy might be effective for patients with ICVD.
出处 《齐鲁医学杂志》 2003年第3期247-248,共2页 Medical Journal of Qilu
关键词 缺血性脑血管病 SIL-2R ELISA法 免疫组织化学 检测 cerebrovascular disorder receptor, interleukin-2 immunohistochemistry
  • 相关文献

参考文献12

  • 1杜群军,石锐,张文玉,谭岩.脑血栓患者外周血T淋巴细胞亚群的初步研究[J].中风与神经疾病杂志,1992,9(2):118-118. 被引量:6
  • 2周善人 王辉.免疫与脑血管病[J].中华神经精神科杂志,1986,9(1):52-52.
  • 3Rubin LA,Smith A.Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro [J].Immunol,1995,135:3172.
  • 4Hess DC,Rstrom B,Bjorn AN,et a1.Stroke associated with antiphosphoI;pid antibodies[J].Stroke,1992,23(2):123.
  • 5Stranchen JA,Rostrom B,Gentics SR,et al.Interleukin receptors in lymphoid lession relavance to diagnosis[J].Biology and Therapy,Pathol Annu,1989,24(pt2):149.
  • 6Laughnan MS,Levine WJ,Calhoun AD,et al.Soluble interleukin-2 receptors are released from the cell Surface of normal murine Bly B lymphocytes stimulated with interleukins[J].Pro Natl Acad Sci USA,1988,14:283.
  • 7Nelson DL,Reem G.Expression of soluble form of IL-2 receptor and neoplastic status[J].Ann Internal Med,1986,105:560.
  • 8Diamantstein T,Diaman F,Harris ER,et al.The interleukin 2 receptor: its physiology and a new approach to selective immunosuppression therapy by anti-interleukin 2 receptor monoclonal antibodies[J].Immunol Rev,1986,92:5.
  • 9Semenzatol G,Youth HG,Cross B,et al.T cell growth factor receptors[J].Exp Med,1981,154: 1455.
  • 10Levine SR,Findley HM,Kilmo,et al.Risk of recurrebt thromb-embolic events in patients with focal cerebral ischemic and antiphospholipid antibodies[J].Stroke,1992,23(2):129.

共引文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部