摘要
①目的 探讨青岛市市区耐甲氧西林金黄色葡萄球菌 (MRSA)临床分布及耐药特征 ,指导临床合理用药。②方法 对 2 0 0 0～ 2 0 0 2年青岛市 7家医院分离出的 32 4株MRSA的临床分布进行回顾性分析 ,并以API Staph系统进行鉴定和耐药性分析。 ③结果 MRSA占葡萄球菌的 15 .71% ,占金黄色葡萄球菌 (SA)的 5 7.14 %。MRSA对临床常用抗生素具多重耐药性 ,耐药率远远高于甲氧西林敏感金黄色葡萄球菌 (χ2 =8.2 8～ 13.14 ,P <0 .0 1)。MRSA分布侧重于烧伤科、肿瘤科、呼吸内科、神经内科、胸外科、ICU及骨外科等病房 ,主要存在于创面分离物、引流液、痰、血、中段尿等送检标本。④结论 2 0 0 0～ 2 0 0 2年MRSA分离率有逐年上升的趋势 ,且耐药谱广 。
Objective To study the distribution and drug resistance of methicillin-resistant Staphylococcus aureus ( MRSA) isolated from Qingdao city, to guide reasonable use of antibiotics clinically. Methods API-Straph detection system was used to identify and analyze 324 MRSA samples obtained from seven hospitals in Qingdao during 2000-2002. A retrospective study was done for its clinical distribution. Results MRSA accounted for 15.71% in Staphylococcus and 57.14% in Staphylococcus aureus(SA). MRSA had multi-resistance to antibiotics that commonly used clinically and its tolerance rate was much higher than that of methicillin-sensitive Staphylococcus aureus(χ 2=8.28-13.14,P<0.01). The samples were mainly isolated from wards of burn, oncology, respiratory diseases, neurology, thoracic surgery, ICU and orthopedics. Conclusion The isolation rate of MRSA from year 2000 to 2002 was increasing from year to year, the tolerance spectrum was broad. To which great attention should be paid.
出处
《齐鲁医学杂志》
2003年第4期385-387,共3页
Medical Journal of Qilu
基金
青岛市科技局资助项目 (青科技字 [2 0 0 0 ] 178号 )
