睡眠呼吸暂停综合征生存质量影响因素分析

The Risk Factors Affecting the QOL of OSAS Patients and the Influence of nCPAP Treatment on the QOL of OSAS Patients

目的 探讨睡眠呼吸暂停综合征对生存质量的影响因素。方法 采用WHOQOL -BREF生存质量量表对 2 12例OSAS患者进行生存质量测评 ,比较嗜睡、睡眠质量、慢性病对患者生存质量的影响和经鼻持续气道正压通气 (nCPAP)治疗后的改变。结果 OSAS患者生存质量生理领域、心理领域得分均值均为嗜睡组低于不嗜睡组、睡眠质量差组低于睡眠质量好组 (P均 <0 0 1) ;生理、心理、社会、环境四个领域的评分均为伴有慢性病组低于不伴有慢性病组 (P <0 0 1和P <0 0 5 ) ;nCPAP治疗后生存质量总分比治疗前明显提高 (P <0 0 1) ,嗜睡评分和睡眠质量评分比治疗前有明显降低 (P <0 0 1)。结论 OSAS患者的嗜睡、低睡眠质量及慢性病是影响生活质量的因素 ,nCPAP治疗能改善白天嗜睡和睡眠质量 ,提高患者生存质量。

Objective To explore the risk factors affecting the quality of life (QOL) of patients with obstructive sleep apnea (OSAS) and the influence of nasal continual positive airway pressure (nCPAP) treatment on the QOL of OSAS patients. Methods Measuring the quality of life of 212 patients suffered from OSAS with WHOQOL-BREF and analyzing the influences of the sleepiness, quality of sleep, chronic disease and nCPAP treatment on the QOL of patients with OSAS. Results The scores on physical domain and psychological domain of patients who were sleepiness or had bad quality of sleep were less than that of patients who were non-sleepiness or had a good sleep respectively(P<0 01). The patients with chronic disease had lower score on physical, psychological, social, environmental domains than that of the patients without chronic diseases.The total score of QOL of the patients after nCPAP treatment was more than that before nCPAP treatment. The scores of sleepiness and quality of sleep after nCPAP treatment were less than that before nCPAP treatment. Conclusions The sleepiness, quality of sleep, chronic diseases can affect the QOL of patients with OSAS. nCPAP treatment can amend the quality of sleep and improve the QOL of the patients.