重点初治涂阳肺结核病人规范管理方法探讨

Study on the management on special new smear-positive pulmonary tuberculosis patients

目的 探索适合重点初治涂阳肺结核病人的管理方式。方法 选取初治涂阳肺结核病人 ,对重点初治涂阳病人实行规范管理 ,称规范管理组 ,其余实施全程督导 ,称全程督导组 ,两组均采用初治涂阳肺结核病人短程化疗方案 ( 2HRZE/4H 3R 3 ) ,并采用板式组合药 ,观察两种管理方式下病人的疗效及中断治疗情况。结果 规范管理组和全程督导组 2个月痰菌阴转率分别为 97 8%和 97 4% ,疗程结束治愈率分别为 95 6%和 96 6% ,断药率分别为 0 3 %和 0 19% ,差异均无显著性(P >0 .0 5 )。结论 家庭督导式规范管理可获得与以医生为主体的全程督导同样的效果。

To explore a suitable method of managing special new smear-positive pulmonary tuberculosis patients. Special new smear-positive pulmonary tuberculosis patients were selected and divided into two groups: standardized family-administrative group and directly observed group. Both groups received short-term chemotherapy (2 HRZE/4 H3R3) and panel combination drugs. The curative effect and the situation in interrupted treatment of the two groups were observed. Sputum conversion rate of the two groups were 97.8% and 974% respectively. Cure rate were 95.6% and 96.6% respectively. Interrupted treatment rate were 0.3% and 0.19% respectively. No significant difference was found (P>0.05).[Conclusion] The same effectiveness can be gained from standardized family-administration method and directly observation method.