摘要
目的 :对阿昔洛韦与西咪替丁在氯化钠输液中配伍稳定性进行考察。方法 :用紫外分光光度法测定配伍液中阿昔洛韦、西咪替丁的含量 ,并观测配伍液外观、p H值。结果 :配伍实验表明 ,配伍液在 4小时内 p H、含量无明显改变 ,且 4小时配伍溶液紫外扫描与 0时刻比较 ,峰形均无明显变化。结论 :阿昔洛韦可与西咪替丁在 0 .9%氯化钠注射液中配伍 。
Objective: To investigate the compatible stability of Acyclovic and Cimetidine in sodium chloride injection. Methods: The content of Acyclovic and Cimetidine in mixed solution was determined by UV method, the appearance and the pH of the mixed solutions were observed. Result: There were no obvious changes in the pH and the content of Acyclovic and there was no apparent change between the formation of the peak from UV scanning pattern of 0h and 4h. Conclusion: Acyclovic could be mixed with cimetidine in sodium chloride injection, but it should be used up within some hours.
出处
《天津药学》
2003年第4期19-20,共2页
Tianjin Pharmacy
关键词
阿昔洛韦
西咪替丁
稳定性
配伍
Acyclovic, Cimetidine, Stability, Compatibility
