影响判断肺部孤立性小结节良恶性因素的logistic回归分析

The factors affecting to judge the solitary pulmonary nodule benign or malignant by logistic regression model

目的 探讨影响判断肺部孤立性小结节(solitary pulmonary nodule,SPN)良恶性的因素。方法 对本院近10年来150例肺部孤立性小结节进行研究。选择18个可能影响临床医生判断的因素,应用SPSS10.0程序进行二维logistic回归分析。结果 150例肺部孤立性小结节中恶性78例(52％),良性72例(48％),判断其良恶性的主要因素是:年龄,吸烟量,SPN有无毛刺、分叶,密度是否均匀。结论 病人的年龄,吸烟量,影像学特征(SPN有无毛刺、分叶、密度是否均匀)对判断SPN良恶性有重要意义。

Objective To explore the factors which affect to judgement of SPN's benign or malignant. Methods 150 cases with SPN hospitalized from Jan 1990 to July 2000 were reviewed. 18 factors which maybe mostly affecting the doctor to judge the SPN is benign or malignant were selected. A multi - variate analysis of these individual variables was performed by the computer's logistic regression model. Results There were 78 malignant SPN cases (52% ) and 72 benign SPN (48% ) in all 150 cases. The results showed that the major risk factors that affect to judge the SPN benign or malignant were amount of smoking, age, character of image (if the SPN have thorn, segmented, or the density is not mean) . Conclusion Amount of smoking, age, character of image (if the SPN have thorn, segmented, or the density is not mean) can help the doctor to judge the benign or malignant SPN.