女性丛集性头痛的临床特点观察

Clinical characteristics of female patient with cluster headache

目的探讨女性丛集性头痛(CH)的临床特点、合并症状及诊断标准。方法对23例女性CH患者(1990-03～2001-11)和同期随机选择的40例男性患者进行对比分析。结果女性有20～29岁和50～59岁两个高发病年龄段,男性仅30～39岁一个高发病年龄段;女性CH头痛持续时间稍短于男性;有6例女性患者在20岁左右和30岁左右有过3～4次典型发作,直到50岁后才发展达到诊断标准。女、男患者有约50%左右的合并恶心、呕吐、畏光或恐响症。结论女性CH临床特点除头痛发作持续时间短于男性外,其他特点无显著性差异(P>0.05);发病年龄女性有两个高发病年龄段;CH患者约有40%～80%的在发作时合并恶心、呕吐、畏光和恐响症,这4项症状被排除诊断标准外有可能降低CH的流行病学结果,部分女性病例需较长时期发展到诊断标准。

Objective To probe into the clinical characteristics, associated symptoms and diagnosis standard. Method The 23 female patleuts with cluster headache (CH) were assembled; their clinical features and onset process were observed, and compared with 40 male patients with CH, who were selected random at same term. Results For female, there were two age-segments of high incidence(20-29 years and 50-59 years), but for male only one (30-39 years); the headache continuation duration of female patients was longer than that of male patients. At the age-segment (about 20, and 30 years), six female patients had 3-4 times of classic onset, but after age of 50 years, their symptom and signs just developed to diagnosis criteria. Both female and male, about 50% of them, were associated with nousea, vomiting, photophobia and soundophobia. Conclusion Except for headache continuation duration, there no significant difference between female and male in clinical features; female has two age-segment of high incidence; the patients with CH, about 40%～80% of them, are associated above foure complicances, if the four symptoms are excepted, the epidemiologic results of CH could be decreased. Besides, it takes for a longer duration that the part of female patients would develop to diagnosis criteria.