硬膜外侧间隙注射胶原酶治疗颈椎椎间盘突出症

Study on cervical disc herniation treatment with cervical epidural lateral interspace collagenase injection

目的探讨硬膜外间隙注射胶原酶治疗颈椎椎间盘突出症的效果。方法分为置管注射法组(组1,60例)和直接注射法组(组2,60例)。组1采用颈部硬膜外侧间隙置管将胶原酶注射到突出的椎间盘周围。组2中,采用颈部硬膜外正中路将胶原酶直接注射到硬膜外后间隙,按外科标准对疗效进行评价。结果组1优良率93%,明显优于组2的47%(P<0.05),两组均无并发症发生。结论颈部硬膜外侧间隙置管注射胶原酶治疗颈椎椎间盘突出症疗效确切,优于直接注射法。

Objective To introduce a method of treating cervical disc herniation with collagenase injection.Mehtods The 120 patients with cervical disc herniation were divided into two groups: implanted tube group(group I) and direct injection group(groupⅡ).In group I, the collagenase was injected into herniated disc through cervical epidural lateral interspace tube. In groupⅡ,it was directly injected into herniated disc. The effect of treatment was evalluated with surgical standard, such as excellent, good, general and poor.Results The rate of both excellent and good were 93%(in group I) and 47%(in group Ⅱ,P<0.05). In two groups,there was no complication founded. Conclusion Cervical disc herniation treatment with cervical epidural lateral interspace implanted tube collagenase injection method is more reliable compared with direct injection method.