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维生素D和多发性硬化 被引量:1

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摘要 维生素D水平变化与多发性硬化的发生有密切的关系,维生素D受体基因多态性与多发性硬化相关。维生素D的活性形式骨化三醇可以预防多发性硬化的模型——实验性变态反应性脑脊髓炎或阻断其进展。对维生素D进行深入研究,对寻找防治多发性硬化的新药具有重要意义。
出处 《国外医学(神经病学.神经外科学分册)》 2003年第4期339-341,共3页 Foreign Medical Sciences(Section On Neurology & Neurosurgery)
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  • 1Nashold FE,Hoag KA,Goverman J,et al.Rag-1-dependent cells are necessary for 1,25-dihydroxyvitamin D(3)prevention of experimental autoimmune encephalomyelitis.J Neuroimmunol,2001,119(1):16-29
  • 2Boonstra A, Barrat FJ, Crain C, et al. 1 alpha, 25- Dihydroxyvitamin D3 has a direct effect on naive CD4 ( + ) T cells to enhance the development of Th2 cells. J Immunol, 2001, 167(9): 4974-4980.
  • 3Matter F,Smiroldo S,Galbiati F,et al.Inhibition of TH1 development and treatment of chronic - relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitmine D(3).Eur J Immunol,2000,30(2):498-508
  • 4Cantorna MT,Hayes CE,Deluca HF.1,25-Dihydroxyvitmine D3 reversibly blocks the progression of relapsing encephalomyelitis,a model of multiple sclerosis.Proc Natl Acad Sci USA,1996,93(15):7861-7864
  • 5Nataf S,Garcion E,Darcy F,et al.1,25-Dihydroxyvitamine D3 exerts regional effects in the central nervous system during experimental allergic encephalomyelitis.J Neuropathol Exp Neurol,1996,55(8):904-914
  • 6Hayes CE, Cantoma MT, Deluca HF. Vitamine D and multiple sclerosis. Proc Soc Exp Biol Med, 1997, 216(1): 21-27.
  • 7Hayes CE. Vitamin D: A natural inhibitor of multiple sclerosis. Proc Nutr Soc, 2000, 59(4): 531-535.
  • 8Elenkov IJ,Wilder RL,Bakalov VK,et al.IL12,TNF-alpha,and hormonal changes during late pregnancy and early postpartum:implications for autoiummune disease activity during these times.J Clin Endocrinol Metab,2001,86(10):4933-4938
  • 9Cosman F,Nieves J,Komar L,et al.Fracture history and bone loss in patients with MS.Neurology,1998,51(4):1161-1165
  • 10Fukazawa T,Yabe I,Kikuchi S,et al.Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanses.J Neurol Sci,1999,166(1):47-52

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