期刊文献+

癫痫的细胞移植现状 被引量:5

原文传递
导出
摘要 癫痫,尤其是难治性癫痫的治疗一直是世界性难题之一。近年来,神经细胞移植为癫痫的治疗带来了新的希望。移植的释放抑制性神经递质的细胞、胚胎海马细胞及神经干细胞等可能与宿主形成了功能上的联系、整合,并在癫痫宿主体内建立新的神经环路,从而抑制癫痫的发生。这些证明神经细胞移植可能将在癫痫治疗的研究中发挥巨大的作用。
出处 《国外医学(神经病学.神经外科学分册)》 2003年第4期389-392,共4页 Foreign Medical Sciences(Section On Neurology & Neurosurgery)
  • 相关文献

参考文献16

  • 1Andres B, Olle L. Cell replacement therapies for central nervous system disorders. Nat Neurosci, 2000, 3(6): 537-544.
  • 2Sotelo C,Alvarado-Mallart RM.The reconstruction of cerebellar circuits.Trends Neurosci,1991,14(8):350-355
  • 3Hernit-Grant CS,Macklis JD.Embryonic neurons transplanted to regions of targeted photolycic cell death in adult mouse somatosensory cortex re-form specific callosal projections.Exp Neurol,1996,139(1):131-142
  • 4Herman JP,Abrous ND.Dopaminergic neural grafts after fifteen years:Results and perspectives.Prog Neurobiol,1994,44(1):1-35
  • 5Buzsaki G,Ponomareef G,Bayardo F,et al.Suppression and induction of epileptic activity by neuronal grafts.Proc Natl Acad Sci USA,1988,85(23):9327-9330
  • 6Gage FH,Dunnet SB,Stenevi U,et al.Aged rats:Recovery of motor coordination impairments by intrastriatal nigral grafts.Science,1983,221(4614):966-969
  • 7Cassel JC,Kelche C,Will BE.Factors influencing structure and function of intracerebral grafts in the mammalian brain:a review.Restor Neurol Neurosci,1992,4(2):65-96
  • 8Tonder N.Neural transplantation to the normal and lesioned brain:An experimental study of the rat hippocampos.Acta Neurol Scand,1995,91(1):6-30
  • 9Zaman V,Tumer DA,Shetty AK.Survival of grafted fetal neural cells in kainic acid lesioned CA3 region of adult hippocampus depends upon cell specificity.Exp Neurol,2000,161(2):535-561
  • 10Davenpory CJ,Brown WJ,Babb TL.Sprouting of GABA ergic and mossy fiber axons in dertate gyrus following intrahippocampal kainite in the rat.Expl Neurol,1990,109(2):180-190

同被引文献55

引证文献5

二级引证文献38

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部