急性感染性二衰重叠的发现及中西医结合防治的创新(上)

The Discovery of Acute Infectious Overlapped Failure and New Concept in Its Treatment and Prevention of Integrated TCM and WM

本文首先阐述20多年前我们是如何发现急性感染性二衰重叠的,进而又探讨为什么过去临床长期普遍容易将白喉周衰误诊误治为中毒性心肌炎的原因,并总结死亡教训,说明内科、儿科等均有必要及早重视急性感染性二衰重叠新理念的重要意义。通过首创中西医结合的“三合一”防治疗法,(1)大胆彻底地修正了119年来国际白喉传统治则,不仅使1978年以后的171例白喉全部治愈,且对比过去入院后再并发心肌炎的发生率,亦明显下降,心肌炎加重而转型的例数明显减少,治愈心肌炎的天数明显缩短,从此结束了南京市传染病医院白喉死亡的院史;(2)实践还证明预防发生二衰重叠的一套治则,可用来避免其他原因引起的感染性休克的死亡及避免周衰后又并发中毒性心肌炎;(3)本文将猪苓汤加减方在研究其治厥机理中所进行的系列多项动物实验基础研究结果,结合现代医学“聚负离子基”结构学说原理,首次总结提出:猪苓汤方中阿胶的多项自我双向调节、动态平衡机理,在抢救二衰重叠时所起的整体性生理性药理机制的独特生命科学意义。因而,本文中、西医两种防治新概念的实践创新,以及两种创新理论的结合,表明不仅通过修正与补充白喉国际传统治则,白喉死亡是可以避免之外,且其他原因引起的急性感染性二衰重叠、周衰。

At the beginning of the article,we explained how to discover the acute inf ectious overlapped failure about more than 20years before,then discussed about the reasons of misdiagnosis and mistreatment of di phtheria peripheral circulatory fa ilure as toxic my-ocarditis readily happened in clini cs for a very long time.We concluded t he lessons from the mortality in diphtheria,and gre atly expected the physicians of inte rnal medicine and pediatrics to pay deep concern about this new concept.We explored an Integrated TCM and WM,three in one,regime in prevention and treatment.(1)Revised thoroughly the worldwide classical therapeutic pr inciple of diphtheria,which had been conducted for119years,thus resulted in complete ly curing of 171cases of diphtheria p atients,and ended the history of patients died fr om diphtheria in Nanjing Hospital of Contagious Disease.In compares with the corresponding data from the days of classical regim e,the incidence of diphtheria myocarditis apparently lowered,and cases with myocarditis de-terioration also diminished,the time span of curing the myocarditis is s hortened.(2)Thereafter,infectious shock and overlapped circulatory failure never happened while we extended this regime further in trea ting other diseases.(3)After the discovery of an an-cient prescription,Umbellate Pore Decoction(猪苓汤),in treating Syncope(厥证),we performed a series of 32items of anim al experiments together with the pol y -anion radical construction theory,and em phasized that Colla Corii Asini (阿胶)in Umbellate Pore Decoction revealed its effect of several self dual regulation and dynamic equilibr ium on treating overlapped failure;showing its pharmacological mechanism possessed physi-ologically the peculiar significan ce in life science.It is concluded th at the innovation and integration of new concepts in both T CM and WM are not merely modified and r enewed the international classical princi ple of diphtheria treatment.Besides the death from diphtheria is evitable,the prognosis of acute infectious overlapped fa ilure from other causes may be improved,too.