1Zhang V, Proenea R, Mallei M, et al. Positional cloning of the mouse obese gene and its human homologue[J]. Nature, 1994,372(6):425-432.
2Considine RV, Sinha MK, Heiman ML, et al. Senum immunoreactive leptin concentrations in normal weight and obese humans[J]. N Engl J Med, 1996,334 (5):292-295.
3Harris RB iZhou J, Redmann SM Jr, et al. A leptin doae-reaponse study in obese(oh/oh) and lean( +/?) mice[J]. Endocrinology, 1998,139(1):8-19.
4Considine RV, Heiman ML, Mueller W, et al. Recombinant leptin and leptin receptor antibodies[J] .Nature Med, 1996,334(5):292-295.
5Mantzoros CS, Tritos NA, Sytephens TW, et al. Nocturnal rise of leptin in lean, obes and non-insulin dependent diabetes mellitus subjects[J].Obes Res, 1998,6(2):179-185.
6Bennelt PA, Linden K, Masuzaki H, et al. Leptin a key player in weight regulation[J]. Neuroendocrinology, 1998,67(1):29-36.
7Mantzoros CS, Tritos NA, Sytephens TW, et al. Nocturnal rise of leptin in lean, obese and non-insulin dependent diabetes mellitus subjects[J]. Obes Res. 1998.6(2):179-185.
8Ffisch RE, Kolaczynski SW, Cosidine RV, et al. Gene play a role in obesity [J].Science, 1980,109(2): 397.
9Fine JB, Fine RM, Sagawa N, et al. The mouse' obesity[J]. Science,1997,36(10):727-728.
10Ford ES,Wiliamson DF, Sinha MK, et al. Leptin blocked by gene in obese people[J]. Physiology, 1997,146(6):214-222.
3Zhang V, Proenea R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue [ J ]. Nature, 1994, 372 ( 6 ) : 425 -423.
4Michael W. Pariza, Yeonhwa Park, Mark E. Cook. Mechanisms of Action of Conjugated Linoleic Acid: Evidence and Speculation [ J]. Society for Experimental Biology and Medicine, 2000, 223: 8-13.
5Brown JM, McIntosh MK Conjugated linoleic acid in humans: regulation of adiposity and insulin sensitivity [ J]. Nutr, 2003, 133 (10) : 3041-3046.
6Rexford S. Ahima, Suzette Y. Osei. Leptin signaling. [J]. Physiology & Behavior, 2004, 81: 223241.
7Kamohara S, Burcelin R, Halaas JL, et al. Acute stimulation of glucose metabolism in mice by leptin treatment [ J]. Nature, 1997, 389: 374 377.
8Cusin I, Zakrzewska KE, Boss O. Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins [J]. Diabetes, 1998, 47:1014 1019.
9Havel PJ. Control of energy homeostasis and insulin action by adipocyte hormones : leptin, acylation stimulating protein, and adiponectin, Curr. Opin. Lipidol, 2002, (13): 51-59.
10Kieffer TJ, Habener JF. The adipoinsular axis. effects of leptin on pancreatic beta-cells, Am [J]. Physiol, 2000 (278): E1-E14.
