重型肝炎和肝炎肝硬化合并感染的临床分析

Clinical analysis of infections complication patients with severe hepatitis or liver cirrhosis

目的 探讨重型肝炎和肝硬化患者合并感染情况及其相关因素。方法 调查 2 86例重型肝炎和肝硬化患者感染发生率、发生部位 ,对其相关因素和预后情况进行分析。结果 感染发生率为 4 7.2 0 % ,其中院内感染发生率为 4 0 .5 6 % ,感染部位以腹膜炎、肠道感染为主 ,分别占 35 .19%和 2 2 .2 2 % ,感染的发生与患者的年龄、抗生素的使用、侵袭性的操作、合并症及病情严重程度有关 ,并直接影响患者死亡率。结论 重型肝炎和肝硬化患者免疫功能低下 ,易并发各种感染而直接影响预后 ,临床上应重点抓住其相关因素 ,减少感染发生 。

Objective To study the infections and their risk factors in patients with severe hepatitis or liver cirrhosis.Methods A prospective survey of the incidence, location,risk factors,and prognosis of infections in 286 patients with severe hepatitis or liver cirrhosis.Results The incidence of infections in patients with severe hepatitis or liver cirrhosis was 47.20%,in which in-hospital infection accounted for 40.56%.A majarity of the infection developed in abdominal cavity and intestinal tract,with incidence rates of 35.19% and 22.22%,respectively.The risk factors were age, use of antibiotics or corticosteroids,improper medical manipulations,severe accompanying disease,and severity of the disease,some of which involved the mortality directly.Conclusions Patients with severe hepatitis or liver cirrhosis are liable to be infected,which affect the prognosis directly.In practice,avoiding the risk factors and reducing the incidence of the infection will improve the prognosis.