抑郁症患者有无自杀行为的临床对照研究

The Control Study of Suicidal Behavior or no Suicidal Behavior with Depression Patients.

目的 了解抑郁症患者的自杀行为。方法 对 1 992～ 2 0 0 3年在洛阳市精神卫生中心及我院住院病例 ,由 2名主治医师对住院病历进行评估。入组条件 :1符合 CCMD-2 -R抑郁发作诊断标准 ;2 HAMD>1 8分 ;3排除脑器质性疾病及躯体精神障碍 ;4无药物滥用及酒精依赖史。符合抑郁诊断病历 2 42例 ,其中男 92例 ,女 1 5 0例 ,有自杀行为者 (简称“自杀组”) 1 0 5例 (占 43 .4% ) ;无自杀组 (简称“无自杀组”) 1 3 7例。结果 自杀组中 ,生活事件作为诱发自杀因素中最为多见 ,两组有显著性差异 (χ2 =1 9.3 42 ,P<0 .0 0 5 ) ;就临床症状而言 ,绝望、自责自罪、焦虑、妄想及早醒等以自杀组显著较多 ( P<0 .0 0 5～ 0 .0 5 ) ,自杀组女性多于男性 ,两组比较有显著性差异 ( P<0 .0 5 ) ,而两组疗效、住院天数及病程无显著差异 ( P>0 .0 5 )。结论 对抑郁症有自杀行为者应进行积极防范和治疗 ,特别对病前有不良生活事件及睡眠障碍 (早醒 )、焦虑、绝望、自责自罪、妄想等症状者 ,应引起社会。

Objective To explore suicidal behavior with depressive patients.Methods 242 patients with depression were divided into two groups.Male are 92 and female 150.Suicidal behavior group(n=105)and no suicidal behavior group(n=173).Results Life events are more than other factor in suicidal behavior group.Suicidal behavior group's female is more than male.There are significant differences in two groups(P<0.05).Conclusion The clinical mental doctor should pay attention to depressive of the suicidal behavior.It's very important that observe the patients carefully and afford effetive therapy.