肺结核合并多脏器功能衰竭危险因素分析

Dangerous Factors Analysis of Pulmonary Tuberculosis Complicated with Multiple Organ Failure

目的 探讨肺结核并发多脏器功能衰竭(MOF)的原因。方法 回顾性总结2422例肺结核并发多脏器功能衰竭的发生率及病死率。结果 97例患者发生肺结核并发多脏器功能衰竭,发生MOF中90.72％为复治肺结核,以呼吸道感染为诱因者占100％,所有病例出现呼吸衰竭,95％出现心衰,肺性脑病占60％。结论 重症肺结核易导致多脏器功能衰竭,病死率随受损器官数目的增多而增高,呼吸道感染是肺结核并发MOF的诱因。

Objective To investigate the causes pulmonary tuberculosis complicated with multiple organ failure(MOF). Methods Incidence and mortality of 2422 cases of pulmonary tuberculosis complicated with multiple organ failure were retrospectively studied. Results 97 patients suffered from pulmonary tuberculosis complicated with multiple organ failure, in which 90.72% were in retreatment. All cases were precipitated by respiratory tract infection. Incidence of pulmonary tuberculosis complicated with respiratory failure were 100% , and complicated with heart failure were 95%, and pulmonary encephalopathy were 60 %. Conclusions Severe pulmonary tuberculosis are liable to progress to multiple organ failure. Mortality is associated with the number of organ failure involved, and mainly precipitated by respiratory tract infection.