黄芪对急性心肌梗死后左心室收缩功能的影响

EFFECT OF ASTRAGALUS MEMBRANACEUS ON LEFT VENTRICULAR SYSTOLIC FUNCTION AFTER ACUTE MYOCARDIAL INFARCTION

目的 探讨黄芪对急性心肌梗死后冠心病患者左心室收缩功能的影响。方法 90例急性心肌梗死患者入选 ,随机分为 3组。分别予以常规治疗、常规治疗 +血管紧张素转换酶抑制剂 (ACEI)、常规治疗 +ACEI +黄芪注射液治疗 3周 ,其后应用经胸壁二维超声彩色多普勒技术检测患者左心室收缩功能。结果 ACEI组和黄芪 +ACEI组患者左室收缩功能较常规治疗组患者显著改善 ,黄芪+ACEI组患者较ACEI组患者心功能改善更为明显 (P <0 .0 5)。结论 黄芪可改善急性心肌梗死后左心室收缩功能。

Objective To investigate the effect of astragalus membranaceus on left ventricular systolic function in patients after acute myocardial infarction (AMI). Methods 90 patients with AMI were enrolled and randomized to 3 groups. They were treated with conventional therapy, conventional therapy plus angiotensin converting enzyme inhibitor(ACEI),conventional therapy plus ACEI and astragalus membranaceus injection for 3 weeks, respectively. The left ventricular systolic functions were measured by 2-dimension color Doppler echocardiography after treatment. Results The left ventricular systolic functions improved significantly in patients treated by ACEI and ACEI plus astragalus membranaceus injection compared to patients by conventionally. In comparison to ACEI-treated group, the left ventricular systolic function improved significantly in group treated by ACEI plus astragalus membranaceus injection(P<0.05). Conclusion Astragalus membranaceus is beneficial to improve left ventricular systolic function in patients after AMI.