肠杆菌科细菌产超广谱β-内酰胺酶菌株的检测及分析

The test and analysis of ESBLs bacterial strain produced by bacteria of intestinal bacillus family

目的 探讨肠杆菌科细菌超广谱β-内酰胺酶(ESBLs)产生情况及耐药性。方法 对临床检出225株肠杆菌科细菌分别应用肠杆菌科细菌生化编码微量鉴定管鉴定、β-内酰胺酶(BLs)检测、标准筛选、双纸片法进行确证及药物敏感实验等方法进行检测分析。结果 225株肠杆菌科细菌中共检出产ESBLs菌26株，主要分布于高干科ll株(42．3％)、神经内科7株(26．9％)、呼吸内科4株(15．4％)、心胸泌尿外科3株(11．5％)；药敏实验结果除对亚胺培南、舒普深未产生耐药外，对其他15种抗生素均出现不同程度耐药，其中9种耐药率为100％。结论 肠杆菌科细菌产ESBLs菌株具有很强的耐药性。

Objective To investigate the production and drug resistance of ESBLs in the bacteria of intestinal bacillus. Methods 225 strains of bacteria of intestinal bacillus family discovered clinically were identified through biochemical coding micro-identifying test tube of bacteria of intestinal bacillus family, tested through BLs, screened standardly, confirmed through double-paper method, and tested and analyzed through drug sensitivity test. Results In 225 strains of bacteria of intestinal bacillus family,26 st...