肝硬化肾损害尿微量蛋白的检测结果分析

Analysis of the test results of urinary micro-protein in renal damage caused by cirrhosis

目的 探讨肝硬化时肾损害尿微量蛋白测定的临床意义。方法 应用放射免疫技术(RIA)测定肝硬化患者尿中微量清蛋白(m-AIb)、β2-微量球蛋白(β2-MG)、α1-微球蛋白（α1-MG）、免疫球蛋白G(IgG)的含量。结果 肝硬化患者随着病情的加重，尿中上述4种微量蛋白呈梯度增高，与对照组比较具有非常显著性差异(P<0．01)；肝硬化各期功能之间均具有显著性差异(P<0．05)；结论 肝硬化早期尿微量蛋白增高标志着肾小球、肾小管结构和功能已有病理性损害。

Objective To study the clinical significance of detection of urinary micro-protein in renal damage caused by cirrhosis. Methods The contents of m-AIb, β2-MG, α1-MG, and G(IgG) in urine of patients were detected through RIA. Results Gradient increase of the 4 micro-proteins could be found in the urine of the patients with their conditions becoming severe and there was significant difference ( P < 0.01) in comparison with the control group; there was significant difference ( P < 0.05) in the liver function of...