利培酮治疗老年期器质性精神障碍21例

Risperidone in the Treatment of 21 Senile Patients with Organic Psychonosema

目的:探讨利培酮治疗老年期器质性精神障碍的用药特点、疗效及不良反应。方法:调查分析21例以利培酮治疗4周以上、年龄>60岁的老年期器质性精神障碍住院患者。利培酮的平均起始剂量为(0.72±0.26)mg·d-1,平均治疗剂量(1.58±0.83)mg·d-1。结果:本组患者总有效率85.7％,不良反应发生率23.8％。结论:利培酮治疗老年期精神障碍疗效好、剂量低。

Objective:To probe into the scheme of medication, therapeutic effectiveness and adverse reactions of risperidone in the treatment of senile organic psychonosema. Method:21 in-patients with senile organic psychonosema were treated with resperidone for more than 4 weeks. All these patients were over 60 years of age. The average initial dose of risperidone was (0.72±0.26) mg·d-1 , po, the average therapeutic dose, (1. 58 ± 0. 83) mg· d-1 , po. Results: The overall effective rate was 85. 7%, the incidence of adverse reactions was 23.8% . Conclusion: Risperidone was shown to have fairly good therapeutic effects in the treatment of senile organic psychonosema, and the dose required was low.