潜阳定眩饮治疗阴虚阳亢型高血压病的疗效观察

Therapeutic Effect of Qianyang Dingxuan Decoction for Hypertension with Yin Deficiency and Yang Hyperactivity

[目的]观察潜阳定眩饮(主要由石决明、生牡蛎、生龙骨、珍珠母、葛根、夜交藤、白芍、竹茹、桑寄生、钩藤、熟地、黄芩、天麻、牛膝、杜仲、僵蚕等中药组成)治疗阴虚阳亢型高血压病的疗效。[方法]以潜阳定眩饮治疗高血压病60例,另设阳性对照组30例(服用马来酸依那普利片和阿斯匹林肠溶片),比较两组症状疗效。[结果]治疗组总有效率93.3％,对照组总有效率76.7％,治疗组疗效优于对照组(P<0.05)。两组治疗后收缩压(psystolic)、舒张压(pdiastolic)均比治疗前降低(P<0.05),但两组降压疗效无显著性差异(P>0.05);在症状疗效方面,治疗组总有效率高于对照组(P<0.05)。[结论]提示潜阳定眩饮降血压效果与马来酸依普利片加阿斯匹林肠溶片相仿,在改善症状方面优于对照组。

[Objective] To observe the therapeutic effect of Qianyang Dingxuan Decoction (QDD) for hypertension with yin deficiency and yang hyperactivity. QDD is mainly composed of Concha Haliotidis, Ostrea, Os Draconis, Concha Margaritifera Usta, Caulis et Folium Polygoni Multiflori, Radix paenonicae Alba, etc.. [Methods] Sixty cases (Group A) of essential hypertension were treated with QDD and 30 were in positive control group (Group B). Therapentic effect in the two groups were compared. [Results] The total effective rate was 93.3% in Group A and 76.7% in Group B, the difference being significant ( P < 0.05 ) . Systolic pressure ( SP) and diastolic pressure ( DP) in Group A before treatment differed from those after treatment (P < 0.05) and the differences of SP and DP were insignificant between Group A and Group B ( P > 0.05). Effect of QDD in relieving symptoms was superior to Group B ( P < 0.05). [Conclusion] It is indicated that QDD has a certain effect in decreasing blood pressure and especially in relieving symptoms.