肺癌的纤维支气管镜刷细胞学诊断分析

A study on cytologic diagnosis of lung carcinoma

目的 通过对肺癌的纤维支气管镜刷细胞学诊断的可靠性和可信性的评价及假阳性诊断的探讨 ,提高细胞学诊断的准确性。方法 将 343例中有组织学对照的 2 13例的细胞学诊断与组织学诊断进行比较分析 ,采用 χ2 检验和四格表 ,计算细胞学诊断的敏感度、特异度、假阳性率、假阴性率及符合率。结果 2 13例细胞学与组织学诊断比较 ,两者差异无显著性 (P >0 .0 5 )。本组细胞学诊断的敏感度94 .5 9% ,特异度 81.5 4 % ,假阳性率 7.89% ,假阴性率 13.11% ,符合率 90 .6 1%。结论 纤维支气管镜刷细胞学是一种诊断肺癌的可靠方法。

Objective To improve the accuracy of cytological diagnosis of smears with fiberoptic bronchoscope brushing cells, and to explore the reliability and false-positive rate of cytological diagnosis. Methods χ 2 test was used to compare the accuracy of cytologic diagnosis of 213 cases with contrasted histopathologic diagnosis. Fish test was used to calculate the sensitivity, specifity, false-positive rate、false-negative rate and accord rate. Results There was no significant difference in the accuracy between cytological and histopathologic diagnosis.In the cytological group, sensitivity was 94.59% , specifity rate was 81.54% , false-positive rate was 7.89% , false-negative rate was 13.11% , and accord rate was 90.61% . Conclusion Cytological diagnosis of fibroptic bronchoscope brushing cells is a reliable method to diagnosis lung cancer.