白细胞对不育男子精液质量的影响

Influence of Leukocyte on Semen Quality of Infertile Men

目的探讨精液中的白细胞对不育男子精液质量的影响。方法本研究采用过氧化物酶染色法检测男子精液中白细胞数量。结果48例标本中,10例精液正常生育者中无一例精液白细胞增多;38例不育者中精液白细胞增多者有31例(>1×106/ml),占81.6％。白细胞阳性者的精子活动率,活动力,尾部肿胀率均显著降低,畸形率和抗精子抗体阳性率明显增高。结论在男性不育患者精液中自细胞数量明显增高,精液白细胞数量的变化可影响精液的质量。

Objective To detect the influence of leukocyte in semen quality of infertile men. Methods Human semen was examined for quantity of leukocyte quality using peroxidase stain. Results The increased leukocyte quantity was not found in the semen of 10 normal fertile men; 31 from 48 infertile patients had an increased leukocyte quantity (over 1 X 106/ml) in their semen, and the semen were analyzed. Leukocyte positive group had significant reduction in sperm motility, viability and sperm tail swelling, but significant increase in morphologic abnormality and antisperm antibodies. Conclusion It is suggested that leukocyte occur frequently in infertile man's semen, the change of leukocyte quantity can influence the semen quality.