甲状腺功能亢进症伴肺动脉高压的超声心动图

Echocardiographic Study of Pulmonary Hypertension in Hyperthyroidism

目的 探讨甲亢腺功能亢进症 (甲亢 )患者肺动脉高压 (PH)的发生与左心结构、功能状态的关系。 方法 应用二维及彩色多普勒超声观察 70例甲亢伴 PH患者左心大小及功能参数、肺动脉收缩压 (SPAP) ,分析SPAP与左心各参数间的相关关系。 结果 (1) 5 3例 (76 % )甲亢伴 PH病例存在左心或全心扩大 ,或伴左室射血分数改变 ;SPAP与左房内径 /主动脉内径值呈正相关 (P<0 .0 1) ,SPAP与性别、年龄、心率、射血分数、左室内径、心输出量等均未见明显相关 (P>0 .0 5 ) ;(2 ) 17例患者并无上述情况或仅伴右心扩大 ,SPAP与上述各变量间无显著相关。 结论 多数甲亢患者的 PH可能与左房扩大有关 ,但部分 PH病例并无左心结构及功能变化 ,提示其

Objective\ To analyze the occurence of pulmonary hypertension and changes of cardiac function in hyperthyroidism patients by echocardiography.\ Methods\ 70 hyperthyroidism patients with pulmonary hypertension(PH) were studied echocardiographically, and the relationship between systolic pulmonary pressure(SPAP) and dimension or performance of left atrial and ventricle was evaluated.\ \{Results\}\ (1)76% patients showed enlargement of left atrial, ventricle or the global heart, decrease of LVEF, and atrial fibrillation.\ Correlation was found between SPAP and LA/AO(r=0 46, P<0 01).\ (2)24% patients showed no echocardiographic changes above, also without correlation between SPAP and other ultrasound parameters.\ Conclusion\ Most PH with hyperthyroidism might related to enlarged left atrium, but some PH which without the changes in heart might have other mechanism.