接受急诊冠状动脉介入治疗的青年与老年急性心肌梗死患者的临床特点及预后分析

Comparison of clinical and angiographic characteristics of young versus aged patients with acute myocardial infarction

目的 评价接受急诊冠状动脉介入 (PCI)治疗的青年与老年急性心肌梗死 (AMI)患者的临床特点与预后的不同。方法 选年龄≤ 5 5岁的青年AMI患者 63名 (组 1)与年龄≥ 65岁的老年AMI患者 85名 (组 2 ) ,比较两组患者的临床特点、造影特点及急诊PCI对其 18± 6 3月随访期预后的影响。结果 青年AMI患者中男性居多 ;老年组患者男女比例接近 (P <0 0 1)。青年组吸烟者多 ,与老年组比较P <0 0 5。青年组高血脂的患病率有高于老年组的趋势。青年组急性心肌梗死多为单支血管病变 ,老年组以多支血管病变居多 (P <0 0 5 )。青年组支架的置入率高于老年组 (P <0 0 1) ,发生再缺血事件及需再血管化的病例在老年组居多 (P <0 0 5 )。结论 青年AMI患者吸烟、高脂血症为其高危因素 :青年AMI患者多为单支血管病变 ,及早PCI可获更佳效益。

Objectives To find the differences in clinical and angiographic characteristics between young and aged patients with acute myocardial infarction treated by primary angioplasty. Methods The coronary risk factors,coronary angiogarphic findings were compared between two groups of patients with AMI:young group(n=63,≤55 years old)and aged group(n=85,≥65 years old). Results This study found that male was predominant over female in young group(P<0.01).Smoking was the most common risk factor in young group(P<0.01)and multivessel disease was more often in aged group(P<0.05).The cardiac function in killip classification on admission was better in the young group than that of aged group(P<0.05). Conclusions Smoking,hypercholesterolemia are the common risk factor in young patients with AMI.The young patients with AMI are prone to single vessel disease,and can get more benefit from early direct angioplasty.