血清肌钙蛋白Ⅰ检测在病毒性心肌炎诊断中的应用

Application of Serum Cardiac Troponin Ⅰ Assay in Diangosis of Viral Myocarditis

目的研究肌钙蛋白Ⅰ(CTnⅠ)在病毒性心肌炎诊断中的应用价值.方法应用定量ELISA法检测血清CTnI,应用生化自动分析仪检测血清肌酸激酶(CK).对40例病毒性心肌炎和30例健康对照组进行对比研究.结果病例组CTnI检测值显著高于对照组(P<0.01);CTnI在血清中存在时间较长,在不同病程中,CTnI异常率高于CK异常率.结论 CTnI可作为病毒性心肌炎的实验室诊断指标,特别是在亚急性期和恢复期有助于病毒性心肌炎的诊断.

ObjectiveTo study the application of CTnI in the diagnosis of vival myocarditis.MethodsDetect serum CTnI by ELISA quantity and serum CK by Automatic Biochemistry analysis instrument. The samples were taken from 40 cases of patients with viral myocarditis and 30 healthy persons were detected as the normal control.ResultsDetecting CTnI of patients was significantly higher than the normal control; CTnI exist quite long time in the serum and abnormal rate of CTnI higher than CK in different course of disease.ConclusionCTnI help to judge viral myocarditis, especially in subacute phase and recover phase.