磷钨酸催化合成丁酮乙二醇缩酮

Catalytic Synthesis of Butanone Glycol Ketal with Phosphowolframic Acid

以磷钨酸H3 PW12 O40 为催化剂 ,通过丁酮和乙二醇反应合成丁酮乙二醇缩酮。探讨了H3 PW12 O40 对缩酮反应的催化活性 ,较系统地研究了酮醇物质的量比、催化剂用量、反应时间等因素对产品收率的影响。实验表明 :H3 PW12 O40 是合成丁酮乙二醇缩酮的良好催化剂 ,在n(酮 )∶n(醇 ) =1∶1.75 ,催化剂用量为反应物料总质量的 1.2 5 % ,环己烷为带水剂 ,反应时间 2 .0h ,反应温度 72～ 96℃的优化条件下 ,丁酮乙二醇缩酮的收率可达 5 9.5 %。

The butanone glycol ketal was synthesized by the reaction of butanone with glycol in the presence of phosphowolframic acid (H 3PW 12O 40) as catalyst . The H 3PW 12O 40 catalytic activity to the ketal reaction was discussed . The influential factors of the molar ratio of ketone and alcohol , catalyst quantity , reaction time etc on the product yield were systematically studied . The experiments showed that the H 3PW 12O 40 is a good catalyst to synthesis of butanone glycol ketal. The yield of butanone glycol ketal can reaches 59.5% under the following optimum conditions:n(butanone)∶n(glycol)=1∶1.75 , the catalyst quantity is equal to 1.25% by mass of the total reaction materials , the cyclohexane is used as water entraining agent , the reaction time is 2.0?h , the reaction temperature is 72～96?℃.