糖尿病人脑血管病发生时的磁共振血管成像特征

MRA features of patients with diabetes during acute cerebral vascular disease

目的 :对 4 3例Ⅱ型糖尿病患者头颅MRA及临床进行分析 ,以探讨Ⅱ型糖尿病患者脑血管改变与病程、临床及预后的关系。方法 :全部病例均行头颅MRI和MRA检查 (Elscint 2 .0 ) ,采用自旋回波序列 ,T1、T2 加权轴位、矢状位和冠状位平扫及MRA检查。结果 :4 3例中发现MRA异常 2 7例 ,主要改变 :①颅内动脉主干的单发和多发性狭窄 ;②血管主干的完全性闭塞 ;③颅内特定部位的血管稀疏区和血管分支的减少 ;④慢性闭塞后的侧枝血管增加 ;⑤动脉粥样硬化造成的血管僵直样改变 ;⑥血管限局性膨大样改变。随病程年限增加MRA异常率亦有上升 ,但临床症候的轻重与MRA有一定关系。结论 :糖尿病患者应用MRA检查有助于对脑血管受损程度进行评估 。

Objective: To analyze MRA and clinical symptoms of 43 cases with diabetes in order to investigate the relation between cerebral vascular changes and the process, symptom and prognosis of cerebral vascular disease. Methods: All the patients were examined by T 1W, T 2W imaging and MRA with 3D-TOF. Results: There were 27 patients with abnormal MRA in 43 cases. The main changes included the stenosis of single or multiple breaches of carotid artery, the obstruction of main breaches, and the reduction of vessels in specific areas. Besides, there happened re-circulation breaches, stiffness changes of vessels from artherosclerosis, and sectional stenosis and expanding. The abnormal rate of MRA was related with the clinical symptoms and suffered duration. Conclusion: It was suggested that the degrees of cerebral vascular lesions be evaluated by MRA,it is of important value in preventing and managing stroke for the patients with diabetes.