4Rochefort H, Garcia M, Glondu M, et al. Cathepsin D in breast cancer: mechanisms and clinical applications, a 1999 overview[ J]. Clin Chim Acta,2000,291 (2) : 157-170.
5Giamarchi C, Solanas M, Chailleux P, etal. Chromatin structure of the regulatory regions of pS2 and cathepsin D genes in hormone-dependent and -independent breast cancer cell lines[ J]. Oncogene, 1999,18(2) :533-541.
6Glikman P, Rogozinski A, Mosto J, et al. Relationship between cathepsin D and other prognostic factors in human breast cancer[ J]. Tumori,1997,83 (3) :685-688.
7Streckfus C, Bigler L, Tucci L, et al. A preliminary study of CA15-3, cerbB-2, epidermal growth factor receptor, cathesin D and p53 in saliva among Women with breast carcinoma [ J ] . Cancer Invest, 2000,18 ( 2 ) :101-109.
8Zheng WQ, Looi LM, Cheah PL. A comparison of the pattern of cathepsin D expression in fibroadenoma, fibrocystic disease, preinvasive and invasive ductal breast carcinoma [ J ]. Pathology, 1999,31 ( 3 ) : 247-251.
9Wright LM, Levy ES, Patel NP, etal. Purification and characterization of cathepsin D from normal human breast tissue[ J ]. J Protein Chem,1997,16(3) : 171-181.
10Roger P, Daures JP, Maudelonde T, et al. Dissociated overexpression of cathepsin D and estrogen receptor alpha in preinvasive mammary tumors[J] .Hum Pathol,2000,31 (5) :593-600.
1Schoenfeld A, Kruger KH, Gomm J, et al. The detection of micrometastases in the peripheral blood and bone marrow of patients with breast cancer using immunohistochemical and reversetranscriptase polymerase chain reaction for Keratin 19 [J]. Eur J Cancer,
2Cote RJ, Rosen PP, Lesser ML, et al. Prediction of early relapse in patients with operable breast cancer by detection of occult bone marrow micrometastases[J]. J Clin Oncol, 1991, 9 (10) :1749-1756
3Diel IJ, Kaufmanu M, Goemer R, et al. Detection of tumour cells in bone marrow of patients with primary breast cancer: a prognostic factor for distant metastasis [J]. J Clin Oncol, 1992, 10(10):1534- 1539
4Cote RJ, Rosen PP, Hakes TB, et al. Monoclonal antibody detect occult breast caroinoma metastases in the bone marrow of patients with early stage disease[J]. Am J Surg Pathol, 1988, 12(5):333 -340
5Slade MJ, Smith BM, Sinnett HD, et al. Quantitative polymerase chain reaction for the detection of micrometastases in patients with breast cancer[J].J Clin Oncol, 1999, 17(3):870-879
6Kim SJ, Ikeda N, Shiba E, et al. Detection of breast cancer micrometastases in peripheral blood using immunomagnetic separation and immunocytochemistry[J]. Breast Cancer, 2001, 8(1), 63 -69
7Solomayer EF, Diel IJ, Meyberg GC, et al . Prognostic relevance of cathepsin D detection in micrometastatic cells in the bone marrow of patients with primary breast cancer [J]. Breast Cancer Res Treat, 1998, 49(2):145～154
8Canavese G, Gipponi M, Catturich A, et al. Technical issue and pathologic implications of sentinel lymph node biopsy in earlystage breast cancer patients[J].J Surg Oncol, 2001, 77(2):81-87
9Steinhoff MM. Axillary node micrometastases: Detection and biologic significance[J]. Breast J, 1999, 5(5): 325-329
