脑卒中后失语症患者认知障碍的影响因素分析

Analysis of Influencing Factors of Cognitive Impairment in Aphasia Patients after Stroke

目的探讨卒中后失语症患者认知障碍的影响因素。方法选择2015年9月～2018年6月我院神经内科收治的脑卒中患者243例,调查患者失语症与认知障碍状况,分析其影响因素。结果所有患者中,失语症76例(31.3%,76/243),其中完全性失语23例,混合性失语17例,感觉性失语20例,运动性失语16例;非失语症患者167例(68.7%,167/243);在失语症患者中有认知障碍约68例,发生率为89.5%(68/76),非失语症患者中有认知障碍8例,发生率为4.8%(8/167),失语症患者认知障碍的发生率显著高于非失语症患者(P<0.05)。失语症与认知障碍的发生率呈极显著正相关(r=0.755,P=0.000)。患者失语症状况、情绪抑郁情况、神经功能损伤程度、血糖水平、病程为影响脑卒中患者认知障碍的影响因素(P<0.05)。结论脑卒中后失语患者较多见,多伴有认知障碍,两者存在显著相关性,失语症程度是认知障碍发生的主要影响因素。

Objective To investigate and analysis the influencing factors of cognitive impairment in patients with aphasia after stroke. Methods From September 2015 to June 2018, 243 stroke patients who were admitted to the Department of Neurology of our hospital were selected. The aphasia and cognitive impairment of all patients were investigated and the influencing factors were analyzed. Results There were 76 patients were aphasia, with the incidence were 31.3% that included 23 patients of complete aphasia, 17 patients of mixed aphasia, 20 patients of sensory aphasia, and 16 patients of motor aphasia. Among the patients with aphasia, 68 patients had cognitive impairment, the incidence rate was 89.5%, and8 patients with non-aphasia had cognitive impairment, the incidence rate was 4.8%. The incidence of cognitive impairment in aphasia patients was significantly higher than that in non-aphasia patients.(P<0.05). Linear correlation analysis showed there were significant positive correlation between aphasia and cognitive impairment(r=0.755, P=0.000). Logistic regression analysis showed that apasia, emotional depression neurological impairment degree, blood glucose and disease duration were the influential factors affected cognitive impairment in stroke patients(P<0.05). Conclusion Patients with aphasia after stroke are more common and more likely to have cognitive impairment. There is a significant correlation between them.Aphasia is the main factor leading to cognitive impairment in patients.