甘精胰岛素治疗老年2型糖尿病合并内科危重患者的临床研究

Clinical Research on Elderly Patients with Type 2 Diabetes Complicated by Medical Critical Illness Treated by Insulin Glargine

目的探讨对老年2型糖尿病合并内科危重疾病患者采用甘精胰岛素治疗,探讨和分析其治疗的临床效果。方法选取该院2011年1月—2013年7月期间收治的110例老年2型糖尿病合并内科危重疾病患者。对照组:对患者采用中性低精蛋白锌人胰岛素进行治疗,可进食的患者,餐前给患者追加短效胰岛素,将患者的血糖浓度控制在5.0~8.0 mmol/L范围内;试验组:在对照组治疗基础上,对患者采用甘精胰岛素治疗。结果经过治疗后,试验组和对照组在1、3、5d的平均血糖浓度分别为(12.1±5.1)mmol/L、(7.6±1.2)mmol/L、(5.5±0.9)mmol/L;(13.4±5.7)mmol/L、(10.8±2.0)mmol/L、(6.6±1.0)mmol/L;结论在临床上,对老年2型糖尿病合并内科危重疾病患者采用甘精胰岛素进行治疗,有效地控制患者的血糖水平,减轻患者的痛苦,提高治疗效果,促进患者的康复,提高患者的生活质量。

Objective To investigate and analyze the clinical effect of insulin glargine on elderly patients with type 2 diabetes complicated by medical critical illness. Methods For patients in the control group, human insulin isophane was given to them and short-acting insulin was also given to the patients who were able to eat before meals for controlling the blood glucose concentration within the range of 5.0~8.0 mmol/L. And insulin glargine was given to the patients in the experimental group on the basis of the treatment given to the control group. Results The average blood glucose concentration of the experimental group and the control group 1, 3, 5d after treatment was (12.1±5.1) mmol/L, (7.6±1.2) mmol/L, (5.5±0.9) mmol/L;(13.4±5.7) mmol/L, (10.8±2.0) mmol/L, (6.6 ±1.0) mmol/L, respectively. Conclusion For elderly patients with type 2 diabetes complicated by medical critical illness in clinical practice, insulin glargine can effectively control the blood glucose level, alleviate the pain, improve the treatment effect, promote the rehabilitation of the patients and enhance the quality of life of the patients.