中药肾毒性的反思

Thinking on Nephrotoxicity in Chinese herbal medicine

就中药关木通、广防己所含马兜铃酸 (AA)的肾毒性和致癌性对国际市场其它中药销售造成负面影响的现状 ,通过中药及国外传统植物药均存在毒性的客观事实 ,阐述了认识天然药物同样有毒副作用的必要性 ;同时以中药雷公藤为例说明必须辩证看待中药作用与副作用的两面性和以复方配伍的优势 ,前瞻性地防治中药肾毒性的可能性 ;最后提出从中药的物种基源把关 。

According to the present condition of Chinese herbal medicine Caulis Aristolochiae Manshuriensis and Tetrandra Root with aristolochine presented nephrotoxicity and carcinogenesis which made a negative influence to the other Chinese herbal medicine saled in international market ,and the objective fact that all of Chinese and abroad traditional herbal medicine exsisted toxic ,the paper expouded the necessity of recognization on side effects also exsisted in natural medicine .At the same time with Tripterygium Wilfordii as a exsample explaned that must dialectical treat the function and side effects of Chinese herbal medicine from both sides and advantages of compatibility of compound medicine. The possibility of prevention and treatment to nephrotoxicity in Chinese herbal medicine . Finally put forward that the emollient measure to prevent nephrotoxicity in Chinese herbal medicine was stricly control the species source of Chinese herbal medicine .